Page 30 - Harnett Life Summer 2020
P. 30

Haley Judd Pulito


         making a difference as a scientist producing medicines



                                                                 Pharmaceutical research wasn’t the plan when Pulito gradu-
                                                                 ated from Lee County High School. At first, she enrolled in a
                                                                 university to study marine biology, but that field wasn’t exactly
                                                                 what she thought it would be. So, she returned home to Sanford
                                                                 and CCCC to complete some university prerequisites and chart
                                                                 a new course.


                                                                 When she arrived in Dr. Rodney Powell’s chemistry class, that
                                                                 direction became clear. “He opened my eyes to chemistry and
                                                                 how much fun it actually was,” she recalled. “I started picking
                                                                 his brain after class and decided to focus my career in chem-
                                                                 istry.” But she didn’t leave her earlier interest behind. Biology
                                                                 teacher Dr. Terry Miller also impressed Pulito with his knowl-
                                                                 edge and enthusiasm. So when both teachers asked her to be-
                                                                 come a student tutor, there was no turning back.


                                                                 After  finishing  her  associate  degree,  Pulito  moved  to  UNC-
                                                                 Greensboro to  take  advantage  of a  well-developed  research
       Central Carolina Community College graduate Haley Judd    program that allowed  her to complete  a research internship
        Pulito is now making a difference in the world at Thermo   with Dr. Terry Nile, helping synthesize molecules used to treat
                          Fisher Scientific.                     cancer. It must have seemed like destiny.
      As everyone grapples with COVID-19, the disease caused by   “I was always interested in how everything worked, especially
      the new coronavirus, the spotlight has suddenly shifted to peo-  in nature — what plants and animals need to survive and how
      ple who once worked in relative obscurity: research scientists   they utilized these nutrients,” she said. “Then, I started getting
      producing vaccines and medicines to treat disease.
                                                                 interested in how humans worked at a chemical level. We’re
                                                                 basically machines. We have all of these different pathways
      Haley Judd Pulito is one of them. She earned her Associate in   and all of those are so interconnected.
      Science at Central Carolina Community College in Sanford be-
      fore completing undergraduate work at the University of North   “It’s all intricate and I wanted to know how all of these work
      Carolina at Greensboro. After moving quickly through some
      entry-level positions, she landed at Thermo Fisher Scientific,   together. I always loved biology and chemistry, so it was per-
      a Fortune 500 biotechnology company, where she is a senior   fect harmonization.”
      scientist for research and development.
                                                                 Her rise to senior research scientist has been fairly fast. Sau-
                                                                 janya Gosangari, R&D formulations manager at Thermo Fish-
      Pulito now lives in Greensboro and works in a laboratory not
      far away in High Point, where she formulates medications, tak-  er Scientific, says Pulito is currently the lead scientist on two
      ing chemical compounds that actively treat a disease and com-  important formulation development projects and provides sup-
                                                                 port for the company’s internal proof-of-concept programs, the
      bining them with other substances needed to create the final   process to show that a new drug is effective and safe.
      product.
                                                                 Gosangari believes Pulito’s success is grounded in a research
      It’s not  as  simple  as  it  sounds. Pulito  formulates  drugs that
      are taken as soft gelatin capsules, which means there are all   environment rich with expert professionals and complex proj-
                                                                 ects that provide an opportunity to learn. But then there are
      sorts of variables to consider. “You have a lot of restrictions   Pulito’s personal characteristics, as well — intelligence, mo-
      and parameters you need to work with and work around,” she   tivation and the abilities to work effectively with people and
      said. “You need to have a drug that is therapeutically effective
      and also must be stable, because it’s sitting on shelves in drug   solve problems using “out-of-the-box thinking.”
      stores and at home. All of the chemical interactions need to   “Her learning curve has been rather fast. She has been able to
      have their proper impact in the end.”

      Page 30                                                                                 Harnett Life ~ Summer 2020
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